Semax

A synthetic heptapeptide based on the ACTH(4-10) fragment, researched for nootropic and neuroprotective effects with particular interest in BDNF upregulation.

What it is

Semax is a short synthetic peptide derived from the 4–10 fragment of adrenocorticotropic hormone (ACTH), extended to improve stability. It belongs to the family of neuro-active research peptides developed in Russia, alongside Selank. Structurally it is a heptapeptide, seven amino-acid residues, and it is studied as a non-hormonal analogue, meaning the ACTH-style hormonal activity of the parent fragment is largely absent.

What the research looks at

In research models Semax is investigated for nootropic and neuroprotective effects, with a recurring focus on upregulation of brain-derived neurotrophic factor (BDNF) and related neurotrophic signalling. Other lines of study look at attention, memory consolidation and resilience under stress. These are laboratory findings only and describe how the compound is researched, not any human use. Supplied strictly for laboratory research use only, not for human or veterinary use.

At a glance

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