CJC-1295 No/DAC
A modified GHRH(1-29) analogue, also called Mod GRF 1-29, studied for shorter, more physiological growth-hormone pulses than its DAC-bearing counterpart.
What it is
CJC-1295 No/DAC, known in the literature as Mod GRF 1-29, is a modified analogue of the first 29 amino acids of GHRH. Without the Drug Affinity Complex (DAC) that extends half-life, the peptide clears more quickly, producing a shorter and more natural-looking release window. It is the GHRH arm of many secretagogue pairings, studied on its own when a closer-to-physiological pulse pattern is the goal.
What the research looks at
Research with this analogue centres on pulse shape: the No/DAC form drives shorter, more physiological GH pulses, which investigators favour when modelling a release pattern closer to the body's own rhythm. Studies look at pulse timing, amplitude and how the modified GHRH(1-29) sequence interacts with the pituitary GHRH receptor. Supplied strictly for laboratory research use only, not for human or veterinary use.
At a glance
| Class | Modified GHRH(1-29) analogue (Mod GRF 1-29) |
| Molecular weight | 3367.9 Da |
| CAS | 863288-34-0 |
| Vial | 5 mg lyophilized |
| Availability | In stock |
Preparing it
The vial ships as a lyophilized powder and is reconstituted with bacteriostatic water (or sterile water for single-session work) before use. Pick a diluent volume that gives a concentration you can read cleanly on a U-100 syringe. See reconstitution for the method and the concentration formula for the maths.