Ipamorelin

A highly selective GH secretagogue and ghrelin mimetic, a pentapeptide studied as a clean tool for GH-axis research because it does not significantly raise cortisol or prolactin.

What it is

Ipamorelin is a selective GH secretagogue and ghrelin mimetic, a short pentapeptide that binds the GH-secretagogue (ghrelin) receptor to trigger growth-hormone release. Its defining feature is selectivity: in research models it prompts GH release without significantly elevating cortisol or prolactin, which is why it is so widely used as the secretagogue arm of GH-axis studies.

What the research looks at

Research on Ipamorelin centres on that selectivity, it is treated as a clean tool for isolating the GH-secretagogue pathway, with studies tracking GH release while confirming the comparatively flat cortisol and prolactin response. Investigators also pair it with GHRH analogues to study receptor synergy. Supplied strictly for laboratory research use only, not for human or veterinary use.

At a glance

Preparing it

The vial ships as a lyophilized powder and is reconstituted with bacteriostatic water (or sterile water for single-session work) before use. Pick a diluent volume that gives a concentration you can read cleanly on a U-100 syringe. See reconstitution for the method and the concentration formula for the maths.

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